US Patent Granted for Novel DNA Detection System

We are pleased to announce the granting of a US patent covering a new deoxyribonucleic acid (DNA) detection system employing electrochemiluminescence (ECL) for the first time, which was developed under a project led by Associate Professor Dr Minhaz Ahmed from the Chemical Sciences Programme of the Faculty of Science, Universiti Brunei Darussalam.


Patent inventors Associate Professor Dr Minhaz Ahmed (Chemical Sciences, Faculty of Science, Universiti Brunei Darussalam) and Dr Sharmili Roy (School of Medicine, Stanford University, United States).


US Patent US10,889,854B2: System and Method for Immobilization Free Electrochemiluminescence DNA Detection using a Luminophore Dye for Multi-Species Detection.


The invention was successfully applied to detect multi-species (porcine and related) and bacillus bacteria DNA. This invention is likely to facilitate various new and improved biosensor applications, both in biomedical and molecular diagnostics. The simplicity of the isothermal DNA amplification and the easy fabrication of this ECL system combined hold significant potential for incorporation into point-of-care devices for food and clinical safety in low-resource areas. The method can also be incorporated into a handheld chip format from different materials such as paper and plastics to make it even more cost-effective. The patent was co-invented by our former PhD student Sharmili Roy, who is currently working as a post-doctoral fellow at the Stanford University School of Medicine in the United States. The work has also been published as a research article in the journal Biosensors and Bioelectronics (Impact Factor 10.2). Full details of the patent can be found here.