Prof. Dr. Abdalla Mohamed Jama

Professor
nb.ude.dbu@amaj.alladba

Portfolio

Educational Qualifications: BSc, MSc, PhD (Stockholm)

Research Interests

  • Gene therapy.
  • Cellular signalling.
  • Molecular basis of disease.

Teaching

  • SB-2241 Cell Biology
  • SB-2243 Introduction to Biochemistry
  • SB-2404 Current Trends in Life Sciences
  • SB-4309 Molecular Genetics

Publications

  • Mohammad, D. K. et al. Dual phosphorylation of Btk by Akt/protein kinase b provides docking for 14-3-3?, regulates shuttling, and attenuates both tonic and induced signaling in B cells. Mol. Cell. Biol. 33, 3214-26 (2013).
  • Hussain, A. et al. Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70. J. Biol. Chem. 288, 7338-50 (2013).
  • Gustafsson, M. O. et al. Regulation of nucleocytoplasmic shuttling of Bruton 's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54). Mol. Cell. Biol. 32, 2440-53 (2012).
  • Hussain, A. et al. TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK. FEBS J. 278, 2001-10 (2011).
  • Hussain, A., Faryal, R., Nore, B. F., Mohamed, A. J. & Smith, C. I. E. Phosphatidylinositol-3-kinase-dependent phosphorylation of SLP-76 by the lymphoma-associated ITK-SYK fusion-protein. Biochem. Biophys. Res. Commun. 390, 892-6 (2009).